Dr MA Majekodunmi was elected into the Nigerian Senate in 1960. He was appointed sole administrator of Western Region in June 1962 after a political crisis in the region, holding office in place of the Premier Samuel Akintola until December that year.[7]
The crisis was due to a struggle between Akintola and the former Western Region Premier and current leader of the opposition Obafemi Awolowo, which had led to violent scenes in the House of Assembly. On advice from the police, one of his first acts was to sign restriction orders to detain leaders of both factions.[7] After the situation had stabilized, Akintola resumed office on 1 January 1963.[8]